2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)butanoic acid - Names and Identifiers
Name | FMOC-DL-2-AMINOBUTYRIC ACID
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Synonyms | FMOC-DL-ABU--OH N-α-Fmoc-norvaline FMoc-2-aMinobutyric acid Fmoc-2-aminobutyric acid DL-Fmoc-Aminobutyric acid MOC-DL-2-AMINOBUTYRIC ACID FMOC-DL-2-AMINOBUTYRIC ACID (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoate (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoate 2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)butanoic acid Butanoic acid, 2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-
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CAS | 174879-28-8
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InChI | InChI=1/C19H19NO4/c1-2-17(18(21)22)20-19(23)24-11-16-14-9-5-3-7-12(14)13-8-4-6-10-15(13)16/h3-10,16-17H,2,11H2,1H3,(H,20,23)(H,21,22)/p-1/t17-/m1/s1 |
2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)butanoic acid - Physico-chemical Properties
Molecular Formula | C19 H19 N O4
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Molar Mass | 325.36 |
Density | 1?+-.0.06 g/cm3(Predicted) |
Boling Point | 550.7±33.0 °C(Predicted) |
Flash Point | 286.8°C |
Vapor Presure | 5.83E-13mmHg at 25°C |
pKa | 3.89±0.10(Predicted) |
Storage Condition | 2-8°C |
2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)butanoic acid - Introduction
FMOC-DL-2-AMINOBUTYRIC ACID, also known as N-(9-fluid aryl) aminobutyric ACID, is an organic compound. Its nature, use, formulation and safety information are described below:
Nature:
FMOC-DL-2-AMINOBUTYRIC ACID is a white to light yellow solid with the property of being easily dissolved in organic solvents. It is an acidic compound that can form salts, has a phenyl protecting group (Fmoc), and can be removed under acidic conditions.
Use:
FMOC-DL-2-AMINOBUTYRIC ACID is widely used in peptide synthesis in organic synthesis. The phenyl protecting group can protect the amino group during the synthesis to avoid non-specific reactions. In the process of peptide synthesis, FMOC-DL-2-AMINOBUTYRIC ACID is often used as a synthetic intermediate to construct the peptide chain, and after synthesis, the desired aminobutyric ACID can be obtained by removing the phenyl protecting group.
Method:
The preparation of FMOC-DL-2-AMINOBUTYRIC ACID is generally achieved by introducing a phenyl protecting group (Fmoc) into 2-aminobutyric ACID. The specific steps include reacting 2-aminobutyric ACID with Fmoc-Cl (chloride of Fmoc group) in a suitable solvent to form FMOC-DL-2-AMINOBUTYRIC ACID, and then obtaining the target product through appropriate purification steps.
Safety Information:
FMOC-DL-2-AMINOBUTYRIC ACID is a chemical, it is necessary to pay attention to safety precautions during use. It may cause irritation to the skin, eyes and respiratory tract, so it is necessary to wear appropriate personal protective equipment, such as gloves, protective glasses and masks. In addition, the compound should be stored and handled away from fire and high temperature to avoid contact with combustibles. In case of contact with skin or eyes, rinse immediately with plenty of water and consult a doctor.
Last Update:2024-04-09 20:52:54